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The VTCRI Center for Transformative Research on Health Behaviors (CTRHB) conducts transformative health behaviors research with the primary objectives of prevention and treatment of life-style related diseases. Our vision, being led by Dr. Warren K. Bickel and Dr. Matthew W. Hulver, is to establish a nationally recognized and federally funded Center of Excellence that focuses on improving health and quality of life in the Commonwealth of Virginia and the Nation. The foci of CTRHB is three-fold – Neurobiological and Decision Making Sciences; Molecular and Clinical Metabolic Sciences; and Implementation, Dissemination, and Health Policy Sciences. This innovative center works to achieve great synergy of research on lifestyle-related diseases with strong collaboration from investigators at the Virginia Tech Carilion Health Sciences and Technology campus in Roanoke, Virginia Tech Carilion Research Institute, faculty in the College of Agriculture and Life Sciences, faculty in the College of Science, and Carilion Clinic. Partnership growth is anticipated with faculty from multiple colleges and institutes, given the broad expanse of the Center’s research interests, from physiology to policy.